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Secondary Structure of Rat and Human Amylin across Force Fields

The aggregation of human amylin has been strongly implicated in the progression of Type II diabetes. This 37-residue peptide forms a variety of secondary structures, including random coils, α-helices, and β-hairpins. The balance between these structures depends on the chemical environment, making am...

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Veröffentlicht in:PLoS One
Hauptverfasser: Hoffmann, Kyle Quynn, McGovern, Michael, Chiu, Chi-cheng, de Pablo, Juan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519342/
https://ncbi.nlm.nih.gov/pubmed/26221949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134091
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