Linaclotide in Chronic Idiopathic Constipation Patients with Moderate to Severe Abdominal Bloating: A Randomized, Controlled Trial

BACKGROUND: Abdominal bloating is a common and bothersome symptom of chronic idiopathic constipation. The objective of this trial was to evaluate the efficacy and safety of linaclotide in patients with chronic idiopathic constipation and concomitant moderate-to-severe abdominal bloating. METHODS: Th...

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Publicado en:PLoS One
Main Authors: Lacy, Brian E., Schey, Ron, Shiff, Steven J., Lavins, Bernard J., Fox, Susan M., Jia, Xinwei D., Blakesley, Rick E., Hao, Xinming, Cronin, Jacquelyn A., Currie, Mark G., Kurtz, Caroline B., Johnston, Jeffrey M., Lembo, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519259/
https://ncbi.nlm.nih.gov/pubmed/26222318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134349
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