Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase.

Uracil-DNA glycosylase (UDG) protects the genome by removing mutagenic uracil residues resulting from deamination of cytosine. Uracil binds in a rigid pocket at the base of the DNA-binding groove of human UDG and the specificity for uracil over the structurally related DNA bases thymine and cytosine...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Kavli, B, Slupphaug, G, Mol, C D, Arvai, A S, Peterson, S B, Tainer, J A, Krokan, H E
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC451908/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8670846/
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