Polarization of the Vacuolar Adenosine Triphosphatase Delineates a Transition to High-Grade Pancreatic Intraepithelial Neoplasm Lesions

OBJECTIVES: A functional vacuolar adenosine triphosphatase (v-ATPase) complex regulates canonical Wnt/β-catenin signaling. The goal of this study was to identify the distribution of the v-ATPase in human and murine models of pancreatic intraepithelial neoplasms (PanINs) and assess its role in Wnt/β-...

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Vydáno v:Pancreas
Hlavní autoři: Sreekumar, Bharath K., Belinsky, Glenn S., Einwachter, Henrik, Rhim, Andrew D., Schmid, Roland, Chung, Chuhan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519037/
https://ncbi.nlm.nih.gov/pubmed/25072283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000201
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