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Evaluation of variant detection software for pooled next-generation sequence data

BACKGROUND: Despite the tremendous drop in the cost of nucleotide sequencing in recent years, many research projects still utilize sequencing of pools containing multiple samples for the detection of sequence variants as a cost saving measure. Various software tools exist to analyze these pooled seq...

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Publicat a:BMC Bioinformatics
Autors principals: Huang, Howard W., Mullikin, James C., Hansen, Nancy F.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518579/
https://ncbi.nlm.nih.gov/pubmed/26220471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0624-y
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