Molecular characterization of systemic sclerosis esophageal pathology identifies inflammatory and proliferative signatures

INTRODUCTION: Esophageal involvement in patients with systemic sclerosis (SSc) is common, but tissue-specific pathological mechanisms are poorly understood. There are no animal scleroderma esophagus models and esophageal smooth muscle cells dedifferentiate in culture prohibiting in vitro studies. Es...

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Published in:Arthritis Res Ther
Main Authors: Taroni, Jaclyn N., Martyanov, Viktor, Huang, Chiang-Ching, Mahoney, J. Matthew, Hirano, Ikuo, Shetuni, Brandon, Yang, Guang-Yu, Brenner, Darren, Jung, Barbara, Wood, Tammara A., Bhattacharyya, Swati, Almagor, Orit, Lee, Jungwha, Sirajuddin, Arlene, Varga, John, Chang, Rowland W., Whitfield, Michael L., Hinchcliff, Monique
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518531/
https://ncbi.nlm.nih.gov/pubmed/26220546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0695-1
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