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Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1

Acute lung injury (ALI) is a severe inflammatory disease for which no specific treatment exists. As glucocorticoids have potent immunosuppressive effects, their application in ALI is currently being tested in clinical trials. However, the benefits of this type of regimen remain unclear. Here we iden...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Vettorazzi, Sabine, Bode, Constantin, Dejager, Lien, Frappart, Lucien, Shelest, Ekaterina, Klaßen, Carina, Tasdogan, Alpaslan, Reichardt, Holger M., Libert, Claude, Schneider, Marion, Weih, Falk, Henriette Uhlenhaut, N., David, Jean-Pierre, Gräler, Markus, Kleiman, Anna, Tuckermann, Jan P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518295/
https://ncbi.nlm.nih.gov/pubmed/26183376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8796
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