Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1

Acute lung injury (ALI) is a severe inflammatory disease for which no specific treatment exists. As glucocorticoids have potent immunosuppressive effects, their application in ALI is currently being tested in clinical trials. However, the benefits of this type of regimen remain unclear. Here we iden...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Vettorazzi, Sabine, Bode, Constantin, Dejager, Lien, Frappart, Lucien, Shelest, Ekaterina, Klaßen, Carina, Tasdogan, Alpaslan, Reichardt, Holger M., Libert, Claude, Schneider, Marion, Weih, Falk, Henriette Uhlenhaut, N., David, Jean-Pierre, Gräler, Markus, Kleiman, Anna, Tuckermann, Jan P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Pub. Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518295/
https://ncbi.nlm.nih.gov/pubmed/26183376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8796
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