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Enhanced anti-ischemic stroke of ZL006 by T7-conjugated PEGylated liposomes drug delivery system

The treatment for ischemic stroke is one of the most challenging problems and the therapeutic effect remains unsatisfied due to the poor permeation of drugs across the blood brain barrier (BBB). In this study, HAIYPRH (T7), a peptide that targeted to transferrin receptor (TfR) can mediate the transp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Wang, Zhongyuan, Zhao, Yue, Jiang, Yan, Lv, Wei, Wu, Lin, Wang, Baoyan, Lv, Lingyan, Xu, Qunwei, Xin, Hongliang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518266/
https://ncbi.nlm.nih.gov/pubmed/26219474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12651
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