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Discovery and Characterization of Nonpeptidyl Agonists of the Tissue-Protective Erythropoietin Receptor

Erythropoietin (EPO) and its receptor are expressed in a wide variety of tissues, including the central nervous system. Local expression of both EPO and its receptor is upregulated upon injury or stress and plays a role in tissue homeostasis and cytoprotection. High-dose systemic administration or l...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Miller, James L., Church, Timothy J., Leonoudakis, Dmitri, Lariosa-Willingham, Karen, Frigon, Normand L., Tettenborn, Connie S., Spencer, Jeffrey R., Punnonen, Juha
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518087/
https://ncbi.nlm.nih.gov/pubmed/26018904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.098400
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