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Identification of a Class of Protein ADP-Ribosylating Sirtuins in Microbial Pathogens

Sirtuins are an ancient family of NAD(+)-dependent deacylases connected with the regulation of fundamental cellular processes including metabolic homeostasis and genome integrity. We show the existence of a hitherto unrecognized class of sirtuins, found predominantly in microbial pathogens. In contr...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Rack, Johannes Gregor Matthias, Morra, Rosa, Barkauskaite, Eva, Kraehenbuehl, Rolf, Ariza, Antonio, Qu, Yue, Ortmayer, Mary, Leidecker, Orsolya, Cameron, David R., Matic, Ivan, Peleg, Anton Y., Leys, David, Traven, Ana, Ahel, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518038/
https://ncbi.nlm.nih.gov/pubmed/26166706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.06.013
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