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Serine is a new target residue for endogenous ADP-ribosylation on histones

ADP-ribosylation (ADPr) is a biologically and clinically important post-translational modification, but little is known about the amino acids it targets on cellular proteins. Here we present a proteomic approach for direct in vivo identification and quantification of ADPr sites on histones. We have...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Leidecker, Orsolya, Bonfiglio, Juan José, Colby, Thomas, Zhang, Qi, Atanassov, Ilian, Zaja, Roko, Palazzo, Luca, Stockum, Anna, Ahel, Ivan, Matic, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113755/
https://ncbi.nlm.nih.gov/pubmed/27723750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2180
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