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Rho-Kinase activity and cutaneous vasoconstriction is upregulated in essential hypertensive humans

Essential hypertension (HT) is associated with endothelial dysfunction augmented vasoconstriction (VC) which may be secondary to increased Rho/Rho-Kinase (ROCK)-dependent mechanisms. Our aim was to assess the in vivo magnitude of cutaneous VC to local cooling as a ROCK specific stimulus, and in vitr...

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Publicado en:Microvasc Res
Autores principales: Smith, Caroline J., Santhanam, Lakshmi, Alexander, Lacy M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517969/
https://ncbi.nlm.nih.gov/pubmed/23481864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2013.02.005
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