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Cyclin E1 deregulation occurs early in secretory cell transformation to promote formation of fallopian tube derived high-grade serous ovarian cancers

Fallopian tube is now generally considered the dominant site of origin for high-grade serous ovarian carcinoma. However, the molecular pathogenesis of fallopian tube-derived serous carcinomas are poorly understood and there are few experimental studies examining the transformation of human fallopian...

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Publicat a:Cancer Res
Autors principals: Karst, Alison M., Jones, Paul M., Vena, Natalie, Ligon, Azra H., Liu, Joyce F., Hirsch, Michelle S., Etemadmoghadam, Dariush, Bowtell, David D. L., Drapkin, Ronny
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517944/
https://ncbi.nlm.nih.gov/pubmed/24366882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2247
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