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A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence

Merkel cell polyomavirus (MCPyV) is considered the etiological agent of Merkel cell carcinoma and persists asymptomatically in the majority of its healthy hosts. Largely due to the lack of appropriate model systems, the mechanisms of viral replication and MCPyV persistence remain poorly understood....

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Theiss, Juliane Marie, Günther, Thomas, Alawi, Malik, Neumann, Friederike, Tessmer, Uwe, Fischer, Nicole, Grundhoff, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517807/
https://ncbi.nlm.nih.gov/pubmed/26218535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004974
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