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Partial inhibition of the ubiquitin–proteasome system ameliorates cardiac dysfunction following ischemia–reperfusion in the presence of high glucose

BACKGROUND: Acute hyperglycemia co-presenting with myocardial infarction (in diabetic and non-diabetic individuals) is often associated with a poor prognosis. Although acute hyperglycemia induces oxidative stress that can lead to dysregulation of the ubiquitin–proteasome system (UPS), it is unclear...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Adams, Buin, Mapanga, Rudo F, Essop, M Faadiel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517635/
https://ncbi.nlm.nih.gov/pubmed/26216448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-015-0258-4
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