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Inadequate ubiquitination-proteasome coupling contributes to myocardial ischemia-reperfusion injury
The ubiquitin-proteasome system (UPS) degrades a protein molecule via 2 main steps: ubiquitination and proteasomal degradation. Extraproteasomal ubiquitin receptors are thought to couple the 2 steps, but this proposition has not been tested in vivo with vertebrates. More importantly, impaired UPS pe...
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| Publicado en: | J Clin Invest |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6264645/ https://ncbi.nlm.nih.gov/pubmed/30204128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI98287 |
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