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The selection and function of cell type-specific enhancers

The human body contains several hundred cell types, all with the same genome. In metazoans, much of the regulatory code that drives cell type-specific gene expression resides in distal elements called enhancers. Enhancers are activated by proteins called transcription factors that bind specific DNA...

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Detalhes bibliográficos
Publicado no:Nat Rev Mol Cell Biol
Main Authors: Heinz, Sven, Romanoski, Casey E., Benner, Christopher, Glass, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517609/
https://ncbi.nlm.nih.gov/pubmed/25650801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3949
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