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Environment drives selection and function of enhancers controlling tissue-specific macrophage identities

Macrophages reside in essentially all tissues of the body and play key roles in innate and adaptive immune responses. Distinct populations of tissue macrophages also acquire context-specific functions that are important for normal tissue homeostasis. To investigate mechanisms responsible for tissue-...

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Dettagli Bibliografici
Pubblicato in:Cell
Autori principali: Gosselin, David, Link, Verena, Romanoski, Casey E., Fonseca, Gregory J., Eichenfield, Dawn Z., Spann, Nathaneal J., Stender, Joshua D., Chun, Hyun B., Garner, Hannah, Geissmann, Frederic, Glass, Christopher K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364385/
https://ncbi.nlm.nih.gov/pubmed/25480297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.11.023
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