Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation?

BACKGROUND: Several c-MET targeting inhibitory molecules have already shown promising results in the treatment of patients with Non-small Cell Lung Cancer (NSCLC). Combination of EGFR- and c-MET-specific molecules may overcome EGFR tyrosine kinase inhibitor (TKI) resistance. The aim of this study wa...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Diagn Pathol
Main Authors: Watermann, I., Schmitt, B., Stellmacher, F., Müller, J., Gaber, R., Kugler, Ch., Reinmuth, N., Huber, R. M., Thomas, M., Zabel, P., Rabe, K. F., Jonigk, D., Warth, A., Vollmer, E., Reck, M., Goldmann, T.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517562/
https://ncbi.nlm.nih.gov/pubmed/26215852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-015-0362-5
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