Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation?

BACKGROUND: Several c-MET targeting inhibitory molecules have already shown promising results in the treatment of patients with Non-small Cell Lung Cancer (NSCLC). Combination of EGFR- and c-MET-specific molecules may overcome EGFR tyrosine kinase inhibitor (TKI) resistance. The aim of this study wa...

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Bibliographic Details
Published in:	Diagn Pathol
Main Authors:	Watermann, I., Schmitt, B., Stellmacher, F., Müller, J., Gaber, R., Kugler, Ch., Reinmuth, N., Huber, R. M., Thomas, M., Zabel, P., Rabe, K. F., Jonigk, D., Warth, A., Vollmer, E., Reck, M., Goldmann, T.
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2015
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4517562/ https://ncbi.nlm.nih.gov/pubmed/26215852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-015-0362-5
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Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation?

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