Thymoquinone enhances cisplatin-response through direct tumor effects in a syngeneic mouse model of ovarian cancer

BACKGROUND: Ovarian cancer is the most lethal gynecologic malignancy characterized by the frequent development of resistance to platinum chemotherapy. Finding new drug combinations to overcome platinum resistance is a key clinical challenge. Thymoquinone (TQ) is a component of black seed oil that ex...

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Vydáno v:J Ovarian Res
Hlavní autoři: Wilson, Andrew J., Saskowski, Jeanette, Barham, Whitney, Yull, Fiona, Khabele, Dineo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517540/
https://ncbi.nlm.nih.gov/pubmed/26215403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-015-0177-8
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