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Genomic approaches to identifying targets for treating β hemoglobinopathies
Sickle cell disease and β thalassemia are common severe diseases with little effective pathophysiologically-based treatment. Their phenotypic heterogeneity prompted genomic approaches to identify modifiers that ultimately might be exploited therapeutically. Fetal hemoglobin (HbF) is the major modula...
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| Publicado no: | BMC Med Genomics |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4517356/ https://ncbi.nlm.nih.gov/pubmed/26215470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-015-0120-2 |
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