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Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers

Sex hormones and their receptors play critical roles in the development and progression of the breast and prostate cancers. Here we report that a novel type of transfer RNA (tRNA)-derived small RNA, termed Sex HOrmone-dependent TRNA-derived RNAs (SHOT-RNAs), are specifically and abundantly expressed...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Honda, Shozo, Loher, Phillipe, Shigematsu, Megumi, Palazzo, Juan P., Suzuki, Ryusuke, Imoto, Issei, Rigoutsos, Isidore, Kirino, Yohei
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517238/
https://ncbi.nlm.nih.gov/pubmed/26124144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510077112
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