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An Overview of Genome Organization and How We Got There: from FISH to Hi-C
In humans, nearly two meters of genomic material must be folded to fit inside each micrometer-scale cell nucleus while remaining accessible for gene transcription, DNA replication, and DNA repair. This fact highlights the need for mechanisms governing genome organization during any activity and to m...
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| Veröffentlicht in: | Microbiol Mol Biol Rev |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4517094/ https://ncbi.nlm.nih.gov/pubmed/26223848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00006-15 |
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