Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms

The 5-HT(3) receptor is a ligand-gated ion channel, which is expressed in the nervous system. Its antagonists are used clinically for treatment of postoperative- and radiotherapy-induced emesis and irritable bowel syndrome. In order to better understand the structure and function of the 5-HT(3) rece...

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Bibliografske podrobnosti
izdano v:Toxins (Basel)
Main Authors: Otvos, Reka A., Krishnamoorthy Iyer, Janaki, van Elk, René, Ulens, Chris, Niessen, Wilfried M. A., Somsen, Govert W., Kini, R. Manjunatha, Smit, August B., Kool, Jeroen
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516916/
https://ncbi.nlm.nih.gov/pubmed/26114334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7072336
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