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Therapeutic antiviral T cells noncytopathically clear persistently infected microglia after conversion into antigen-presenting cells

Several viruses can infect the mammalian nervous system and induce neurological dysfunction. Adoptive immunotherapy is an approach that involves administration of antiviral T cells and has shown promise in clinical studies for the treatment of peripheral virus infections in humans such as cytomegalo...

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Détails bibliographiques
Publié dans:J Exp Med
Auteurs principaux: Herz, Jasmin, Johnson, Kory R., McGavern, Dorian B.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516789/
https://ncbi.nlm.nih.gov/pubmed/26122661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20142047
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