The Mitochondrial Uncoupler DNP Triggers Brain Cell mTOR Signaling Network Reprogramming and CREB Pathway Upregulation

Mitochondrial metabolism is highly responsive to nutrient availability and ongoing activity in neuronal circuits. The molecular mechanisms by which brain cells respond to an increase in cellular energy expenditure are largely unknown. Mild mitochondrial uncoupling enhances cellular energy expenditur...

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Publicat a:J Neurochem
Autors principals: Liu, Dong, Zhang, Yongqing, Gharavi, Robert, Park, Hee Ra, Lee, Jaewon, Siddiqui, Sana, Telljohann, Richard, Nassar, Matthew R., Cutler, Roy G., Becker, Kevin G., Mattson, Mark P.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516713/
https://ncbi.nlm.nih.gov/pubmed/26010875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13176
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