Inhibiting Inducible Nitric Oxide Synthase in Enteric Glia Restores Electrogenic Ion Transport in Mice with Colitis

BACKGROUND & AIMS: Disturbances in the control of ion transport lead to epithelial barrier dysfunction in patients with colitis. Enteric glia regulate intestinal barrier function and colonic ion transport. However, it is not clear whether enteric glia are involved in the epithelial hypo-responsi...

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Publicat a:Gastroenterology
Autors principals: MacEachern, Sarah J., Patel, Bhavik A., Keenan, Catherine M., Dicay, Michael, Chapman, Kevin, McCafferty, Donna-Marie, Savidge, Tor C., Beck, Paul L., MacNaughton, Wallace K., Sharkey, Keith A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516675/
https://ncbi.nlm.nih.gov/pubmed/25865048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.04.007
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