Adrenomedullin promotes differentiation of oligodendrocyte precursor cells into myelin-basic-protein expressing oligodendrocytes under pathological conditions in vitro

Oligodendrocytes, which are the main cell type in cerebral white matter, are generated from their precursor cells (oligodendrocyte precursor cells: OPCs). However, the differentiation from OPCs to oligodendrocytes is disturbed under stressed conditions. Therefore, drugs that can improve oligodendroc...

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Veröffentlicht in:Stem Cell Res
Hauptverfasser: Maki, Takakuni, Takahashi, Yoko, Miyamoto, Nobukazu, Liang, Anna C., Ihara, Masafumi, Lo, Eng H., Arai, Ken
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516627/
https://ncbi.nlm.nih.gov/pubmed/26002630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2015.05.001
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