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Visualizing CTL/melanoma cell interactions: multiple hits must be delivered for tumour cell annihilation

It is well established that cytotoxic T lymphocytes (CTL) can kill target cells offering a very small number of specific peptide/MHC complexes (pMHC). It is also known that lethal hit delivery is a very rapid response that occurs within a few minutes after cell–cell contact. Whether cytotoxicity is...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Main Authors: Caramalho, Íris, Faroudi, Mustapha, Padovan, Elisabetta, Müller, Sabina, Valitutti, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Ltd 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516531/
https://ncbi.nlm.nih.gov/pubmed/19017355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00586.x
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