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Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: Manifestation of a dual activation threshold

Activation of biological functions in T lymphocytes is determined by the molecular dynamics occurring at the T cell/opposing cell interface. In the present study, a central question of cytotoxic T lymphocyte (CTL) biology was studied at the single-cell level: can two distinct activation thresholds f...

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Detalhes bibliográficos
Main Authors: Faroudi, Mustapha, Utzny, Clemens, Salio, Mariolina, Cerundolo, Vincenzo, Guiraud, Martine, Müller, Sabina, Valitutti, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC283560/
https://ncbi.nlm.nih.gov/pubmed/14610278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2334336100
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