Infection of Human Liver Myofibroblasts by Hepatitis C Virus: A Direct Mechanism of Liver Fibrosis in Hepatitis C

BACKGROUND: Chronic hepatitis C is a major cause of liver fibrosis and cirrhosis. It is generally accepted that inflammation that occurs in response to hepatocyte infection by the hepatitis C virus (HCV) is the main mechanism that triggers myofibroblast differentiation and stimulation in chronic hep...

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Veröffentlicht in:PLoS One
Hauptverfasser: Aoudjehane, Lynda, Bisch, Grégoire, Scatton, Olivier, Granier, Christelle, Gaston, Jesintha, Housset, Chantal, Roingeard, Philippe, Cosset, François-Loïc, Perdigao, Fabiano, Balladur, Pierre, Wakita, Takaji, Calmus, Yvon, Conti, Filomena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516308/
https://ncbi.nlm.nih.gov/pubmed/26214688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134141
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