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An Enzyme-sensitive PEG Hydrogel Based on Aggrecan Catabolism for Cartilage Tissue Engineering
A new cartilage-specific degradable hydrogel based on photoclickable thiol-ene PEG hydrogels is presented. The hydrogel crosslinks are composed of the peptide, CRDTEGE-ARGSVIDRC, derived from the aggrecanase-cleavable site in aggrecan. This new hydrogel is evaluated for use in cartilage tissue engin...
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| Publicat a: | Adv Healthc Mater |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516272/ https://ncbi.nlm.nih.gov/pubmed/25296398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201400277 |
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