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Enhanced Corneal Absorption of Erythromycin by Modulating P-Glycoprotein and MRP Mediated Efflux with Corticosteroids
PURPOSE: The objectives were (i) to test in vivo functional activity of MRP2 on rabbit corneal epithelium and (ii) to evaluate modulation of P-gp and MRP2 mediated efflux of erythromycin when co-administered with corticosteroids. METHODS: Cultured rabbit primary corneal epithelial cells (rPCECs) was...
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| Gepubliceerd in: | Pharm Res |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516224/ https://ncbi.nlm.nih.gov/pubmed/18958406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-008-9741-x |
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