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Bu-Shen-Ning-Xin decoction: inhibition of osteoclastogenesis by abrogation of the RANKL-induced NFATc1 and NF-κB signaling pathways via selective estrogen receptor α

INTRODUCTION: Bu-Shen-Ning-Xin decoction (BSNXD) is a traditional Chinese medicinal composition that has been used as a remedy for postmenopausal osteoporosis, but the mechanisms affecting bone metabolism are not fully understood. PURPOSE: We investigated the molecular mechanism and signaling pathwa...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Wang, Ling, Qiu, Xue-Min, Gui, Yu-Yan, Xu, Ying-Ping, Gober, Hans-Jürgen, Li, Da-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516212/
https://ncbi.nlm.nih.gov/pubmed/26229438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S88512
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