Ex Vivo Analysis of Human T Lymphotropic Virus Type 1–Specific CD4(+) Cells by Use of a Major Histocompatibility Complex Class II Tetramer Composed of a Neurological Disease–Susceptibility Allele and Its Immunodominant Peptide

HLA-DRB1*0101 is associated with susceptibility to human T lymphotropic virus type 1 (HTLV-1)–associated myelopathy/tropical spastic paraparesis (HAM/TSP). Here, we used a synthetic tetramer of DRB1*0101 and its epitope peptide to analyze HTLV-1–specific CD4(+) T cells ex vivo. The frequency of tetr...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Nose, Hirohisa, Kubota, Ryuji, Seth, Nilufer P., Goon, Peter K., Tanaka, Yuetsu, Izumo, Shuji, Usuku, Koichiro, Ohara, Yoshiro, Wucherpfennig, Kai W., Bangham, Charles R. M., Osame, Mitsuhiro, Saito, Mineki
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515963/
https://ncbi.nlm.nih.gov/pubmed/18190256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/522966
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