In Vivo Selection of T-Cell Receptor Junctional Region Sequences by HLA-A2 Human T-Cell Lymphotropic Virus Type 1 Tax11-19 Peptide Complexes

Using HLA-peptide tetrameric complexes, we isolated human T-cell lymphotrophic virus type 1 Tax peptide-specific CD8(+) T cells ex vivo. Antigen-specific amino acid motifs were identified in the T-cell receptor Vβ CDR3 region of clonally expanded CD8(+) T cells. This result directly confirms the imp...

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Detalhes bibliográficos
Main Authors: Saito, Mineki, Taylor, Graham P., Saito, Akiko, Furukawa, Yoshitaka, Usuku, Koichiro, Weber, Jonathan N., Osame, Mitsuhiro, Bangham, Charles R. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114005/
https://ncbi.nlm.nih.gov/pubmed/11134322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.2.1065-1071.2001
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