In Vivo Selection of T-Cell Receptor Junctional Region Sequences by HLA-A2 Human T-Cell Lymphotropic Virus Type 1 Tax11-19 Peptide Complexes

Using HLA-peptide tetrameric complexes, we isolated human T-cell lymphotrophic virus type 1 Tax peptide-specific CD8(+) T cells ex vivo. Antigen-specific amino acid motifs were identified in the T-cell receptor Vβ CDR3 region of clonally expanded CD8(+) T cells. This result directly confirms the imp...

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Pubblicato in:	J Virol
Autori principali:	Saito, Mineki, Taylor, Graham P., Saito, Akiko, Furukawa, Yoshitaka, Usuku, Koichiro, Weber, Jonathan N., Osame, Mitsuhiro, Bangham, Charles R. M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114005/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.2.1065-1071.2001
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