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The tetracycline destructases: a novel family of tetracycline-inactivating enzymes

Enzymes capable of inactivating tetracycline are paradoxically rare compared with enzymes that inactivate other natural product antibiotics. We describe a family of flavoenzymes, previously unrecognizable as resistance genes, which are capable of degrading tetracycline antibiotics. From soil functio...

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Publicat a:Chem Biol
Autors principals: Forsberg, Kevin J., Patel, Sanket, Wencewicz, Timothy A., Dantas, Gautam
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515146/
https://ncbi.nlm.nih.gov/pubmed/26097034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.05.017
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