The Warburg effect in mycobacterial granulomas is dependent on the recruitment and activation of macrophages by interferon-γ

Granulomas are the hallmark of mycobacterial disease. Here, we demonstrate that both the cell recruitment and the increased glucose consumption in granulomatous infiltrates during Mycobacterium avium infection are highly dependent on interferon-γ (IFN-γ). Mycobacterium avium-infected mice lacking IF...

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Vydáno v:Immunology
Hlavní autoři: Appelberg, Rui, Moreira, Diana, Barreira-Silva, Palmira, Borges, Margarida, Silva, Letícia, Dinis-Oliveira, Ricardo Jorge, Resende, Mariana, Correia-Neves, Margarida, Jordan, Michael B, Ferreira, Nuno C, Abrunhosa, Antero J, Silvestre, Ricardo
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2015
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515130/
https://ncbi.nlm.nih.gov/pubmed/25807843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12464
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