The Warburg effect in mycobacterial granulomas is dependent on the recruitment and activation of macrophages by interferon-γ

Granulomas are the hallmark of mycobacterial disease. Here, we demonstrate that both the cell recruitment and the increased glucose consumption in granulomatous infiltrates during Mycobacterium avium infection are highly dependent on interferon-γ (IFN-γ). Mycobacterium avium-infected mice lacking IF...

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Bibliografiske detaljer
Udgivet i:Immunology
Main Authors: Appelberg, Rui, Moreira, Diana, Barreira-Silva, Palmira, Borges, Margarida, Silva, Letícia, Dinis-Oliveira, Ricardo Jorge, Resende, Mariana, Correia-Neves, Margarida, Jordan, Michael B, Ferreira, Nuno C, Abrunhosa, Antero J, Silvestre, Ricardo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515130/
https://ncbi.nlm.nih.gov/pubmed/25807843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12464
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