Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex

Ups1 forms a complex with Mdm35 and is critical for the transport of phosphatidic acid (PA) from the mitochondrial outer membrane to the inner membrane. We report the crystal structure of the Ups1-Mdm35-PA complex and the functional characterization of Ups1-Mdm35 in PA binding and transfer. Ups1 fea...

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Vydáno v:EMBO Rep
Hlavní autoři: Yu, Fang, He, Fangyuan, Yao, Hongyan, Wang, Chengyuan, Wang, Jianchuan, Li, Jianxu, Qi, Xiaofeng, Xue, Hongwei, Ding, Jianping, Zhang, Peng
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2015
Témata:
Scientific Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515121/
https://ncbi.nlm.nih.gov/pubmed/26071601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540137
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