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The C. elegans Chp/Wrch Ortholog CHW-1 Contributes to LIN-18/Ryk and LIN-17/Frizzled Signaling in Cell Polarity

Wnt signaling controls various aspects of developmental and cell biology, as well as contributing to certain cancers. Expression of the human Rho family small GTPase Wrch/RhoU is regulated by Wnt signaling, and Wrch and its paralog Chp/RhoV are both implicated in oncogenic transformation and regulat...

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Pubblicato in:PLoS One
Autori principali: Kidd, Ambrose R., Muñiz-Medina, Vanessa, Der, Channing J., Cox, Adrienne D., Reiner, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514874/
https://ncbi.nlm.nih.gov/pubmed/26208319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133226
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