A Novel Interaction between FLICE-Associated Huge Protein (FLASH) and E2A Regulates Cell Proliferation and Cellular Senescence via Tumor Necrosis Factor (TNF)-Alpha-p21WAF1/CIP1 Axis

Dysregulation of the cell proliferation has been implicated in the pathophysiology of a number of diseases. Cellular senescence limits proliferation of cancer cells, preventing tumorigenesis and restricting tissue damage. However, the role of cellular senescence in proliferative nephritis has not be...

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Publicat a:PLoS One
Autors principals: Hirano, Takahiro, Murakami, Taichi, Ono, Hiroyuki, Sakurai, Akiko, Tominaga, Tatsuya, Takahashi, Toshikazu, Nagai, Kojiro, Doi, Toshio, Abe, Hideharu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514670/
https://ncbi.nlm.nih.gov/pubmed/26208142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133205
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