The Influence of the Autoimmunity-Associated Ancestral HLA Haplotype AH8.1 on the Human Gut Microbiota: A Cross-Sectional Study

Multiple immune-related genes are encoded in the HLA complex on chromosome 6p21. The 8.1 ancestral haplotype (AH8.1) include the classical HLA alleles HLA-B*08:01 and HLA-DRB1*03:01, and has been associated with a large number of autoimmune diseases, but the underlying mechanisms for this associatio...

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Publicat a:PLoS One
Autors principals: Hov, Johannes R., Zhong, Huanzi, Qin, Bingcai, Anmarkrud, Jarl Andreas, Holm, Kristian, Franke, Andre, Lie, Benedicte A., Karlsen, Tom H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514645/
https://ncbi.nlm.nih.gov/pubmed/26207384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133804
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