Foamy monocytes form early and contribute to nascent atherosclerosis in mice with hypercholesterolemia

OBJECTIVE: To examine infiltration of blood foamy monocytes, containing intracellular lipid droplets, into early atherosclerotic lesions and its contribution to development of nascent atherosclerosis. APPROACH AND RESULTS: In apoE(−/−) mice fed western high-fat diet (WD), >10% of circulating mono...

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Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Xu, Lu, Perrard, Xiaoyuan Dai, Perrard, Jerry L., Yang, Donglin, Xiao, Xinhua, Teng, Ba-Bie, Simon, Scott I., Ballantyne, Christie M., Wu, Huaizhu
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514542/
https://ncbi.nlm.nih.gov/pubmed/26112011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305609
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