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The TNFα/Sphingosine-1-phosphate signaling axis drives myogenic responsiveness in heart failure

Heart failure (HF) is hallmarked by an increase in total peripheral resistance (TPR) that compensates for the drop in cardiac output. While initially allowing the maintenance of mean arterial pressure at acceptable levels, the long term up regulation of TPR is prone to compromise cardiac performance...

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Bibliografiske detaljer
Udgivet i:J Vasc Res
Main Authors: Kroetsch, Jeffrey T., Bolz, Steffen-Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514525/
https://ncbi.nlm.nih.gov/pubmed/23594703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000350528
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