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The TNFα/Sphingosine-1-phosphate signaling axis drives myogenic responsiveness in heart failure

Heart failure (HF) is hallmarked by an increase in total peripheral resistance (TPR) that compensates for the drop in cardiac output. While initially allowing the maintenance of mean arterial pressure at acceptable levels, the long term up regulation of TPR is prone to compromise cardiac performance...

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Detalhes bibliográficos
Publicado no:J Vasc Res
Main Authors: Kroetsch, Jeffrey T., Bolz, Steffen-Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514525/
https://ncbi.nlm.nih.gov/pubmed/23594703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000350528
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