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The TNFα/Sphingosine-1-phosphate signaling axis drives myogenic responsiveness in heart failure
Heart failure (HF) is hallmarked by an increase in total peripheral resistance (TPR) that compensates for the drop in cardiac output. While initially allowing the maintenance of mean arterial pressure at acceptable levels, the long term up regulation of TPR is prone to compromise cardiac performance...
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Publicado no: | J Vasc Res |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4514525/ https://ncbi.nlm.nih.gov/pubmed/23594703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000350528 |
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