ISCOMATRIX™ adjuvant reduces mucosal tolerance for effective pulmonary vaccination against influenza

While most pathogens infect via mucosal surfaces, most current vaccines are delivered by injection. This situation remains despite awareness of the potential benefits of mucosal delivery for inducing protection against mucosa-infecting pathogens. A major obstacle to the development of such vaccines...

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Bibliografiske detaljer
Udgivet i:Hum Vaccin Immunother
Main Authors: Timothy, Andrea A, Tokanovic, Ana, Snibson, Kenneth J, Edwards, Stirling J, Pearse, Martin J, Scheerlinck, Jean-Pierre Y, Sutton, Philip
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
INFLUENZA/Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514340/
https://ncbi.nlm.nih.gov/pubmed/25692970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21645515.2014.990859
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