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ISCOMATRIX™ adjuvant reduces mucosal tolerance for effective pulmonary vaccination against influenza

While most pathogens infect via mucosal surfaces, most current vaccines are delivered by injection. This situation remains despite awareness of the potential benefits of mucosal delivery for inducing protection against mucosa-infecting pathogens. A major obstacle to the development of such vaccines...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Timothy, Andrea A, Tokanovic, Ana, Snibson, Kenneth J, Edwards, Stirling J, Pearse, Martin J, Scheerlinck, Jean-Pierre Y, Sutton, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514340/
https://ncbi.nlm.nih.gov/pubmed/25692970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21645515.2014.990859
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